Central Nervous System Involvement in Whipple Disease
نویسندگان
چکیده
منابع مشابه
Central Nervous System Involvement in Whipple Disease
Whipple disease (WD) is a rare multisystemic infection with a protean clinical presentation. The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, CNS relapse in previously treated WD, and isolated CNS infection. We retrospectively analyzed clinical features, diagnostic workup, brain imaging, cerebrospinal fluid (CSF) study, treatment, and follow-up data i...
متن کاملWhipple disease of the central nervous system.
In 1907, George H. Whipple reported the clinical manifestations and autopsy findings for a patient with the disease that now bears his name [1]. Nearly all of the cardinal clinical manifestations of this disorder—including arthralgias, abdominal pain, fever, diarrhea, malabsorption, weight loss, and cough—were evident in this first patient reported. On the basis of observations of fat and fatty...
متن کاملWhipple disease confined to the central nervous system in childhood.
In a case of pediatric Whipple disease confined to the central nervous system, white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images, and showed slight peripheral enhancement on delayed contrast-enhanced T1-weighted images. On MR studies obtained 3 and 6 months after...
متن کاملCerebellar ataxia and central nervous system whipple disease.
BACKGROUND Whipple disease (WD) is an infectious disease, which may affect the central nervous system. Central nervous system symptoms are eventually present in as many as 43% of the cases. To our knowledge, cerebellar ataxia in WD has never been formally studied in any large series. OBJECTIVE To determine the prevalence of cerebellar ataxia in central nervous system WD. RESULTS Between Jan...
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Systemic Lupus Erythematosus (SLE) is a complex clinical syndrome which its components are less clearly recognized and includes heterogeneous demonstrations engaging both central and peripheral nervous system along with disabling effects. This disease is called "thousand faces" due to these heterogeneous demonstrations. This gap exists while 75% of adults and children with SLE may dea...
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ژورنال
عنوان ژورنال: Medicine
سال: 2013
ISSN: 0025-7974
DOI: 10.1097/md.0000000000000010